The Royal Melbourne Hospital is inviting adults to participate in a research trial involving dietary therapy for epilepsy
Epilepsy affects an estimated 225,000 Australians, with 30% still experiencing seizures whilst on medications. They may be on maximum therapy or are unable to tolerate the side effects of anti seizure medications. There is emerging evidence to show a very low carbohydrate, high fat diet, known as the Modified Atkin's Diet for Epilepsy (MADE), may improve seizure control, with relatively low side e
ffects. This research aims to investigate if Australian adults with epilepsy are able to comply with the dietary modifications of the MADE and to assess if participants experience a reduction in the number of seizures whilst on the diet. Participants will be seen regularly by a Dietitian and Neurologist during clinic visits at the Royal Melbourne Hospital. Additional telephone and email support is also available. Eligibility criteria
• Aged 18-75 years
• Diagnosed epilepsy, experiencing two or more seizures in four weeks
• No changes in epilepsy medication or vagus nerve stimulation (VNS) settings for one month
Ineligibility criteria
• Under 18 years of age
• Body mass index < 18.5kg/m2
• Patients with cluster seizures or who are unable to count or describe their seizures
• Patients experiencing myoclonic or absence seizures only
• Patients experiencing non-epileptic seizures
• Diabetes Mellitus
• Fatty acid or amino acid oxidation disorders
• Pre-existing renal and/or liver failure
• Currently on the ketogenic diet
• Prior history of eating disorders
• Females who are pregnant or breastfeeding
This page provides general advice on the Modified Atkin's Diet for Epilepsy. Individuals should consult their Neurologist and Dietitian for specific recommendations on their condition
