06/02/2026
Early warning system drug alert:
3,4-methylenedioxymethamphetamine (M**A)
INCIDENT SUMMARY
On Wednesday, February 4, 2026, at approximately 10:46 hrs, The Guyana Police, Regional Division #2 responded to a report from a secondary school on the Essequibo Coast where several small transparent zip-lock bags containing a substance suspected to be Methylenedioxymethamphetamine (M**A), commonly known as “Molly,” were discovered in the possession of two students and inside a classroom. The suspected narcotics were seized and weighed, amounting to 5.82 grams, and subsequently lodged as evidence. Two juveniles, aged 14 and 15, were taken to the police station in the presence of school officials, their parents, and a welfare officer, while a 20-year-old male was later arrested and remains in custody as investigations continue.
PRELIMINARY RESULTS
Preliminary Test conducted by Officers confirmed the presence of:
3,4-Methylenedioxymethamphetamine (M**A), A Schedule I controlled substance under the Narcotic Drugs and Psychotropic Substances (Control) Act, Cap. 10:10.
THREAT INDICATORS & EARLY WARNING SIGNALS
• Confirmed circulation of M**A tablets within commercial entertainment zones
• Distribution pattern consistent with nightlife and youth-targeted micro-trafficking
• Amphetamine-type stimulants remain rare in Guyana, making this detection significant
• Potential for increased demand due to nightlife, parties, or imported supply streams
• High-risk profile due to dosing variability and unknown adulterants
WHAT IS METHYLENEDIOXYMETHAMPHETAMINE (M**A)
3,4-methylenedioxymethamphetamine (M**A) is a stimulant and hallucinogen, eliciting an invigorating impact, alterations in temporal and perceptual experiences, and heightened pleasure in tactile sensations.
PUBLIC HEALTH & SAFETY RISKS
• Pills may contain varying concentrations, increasing overdose risk
• Possible adulteration with caffeine, methamphetamine, synthetic cathinones, or other stimulants
Users may experience:
• Rapid heart rate
• Hyperthermia (dangerous overheating)
• Confusion, agitation
• Risk of collapse, seizures, or severe dehydration
• A greater danger when combined with alcohol or other drugs
PSYCHOLOGICAL SIDE EFFECTS AND RISKS OF M**A
• Anxiety and panic attacks
• Confusion
• Depression
• Drug cravings
• Loss of appetite
• Memory and attention difficulties
• Paranoia
• Sleep difficulties
PHYSICAL SIDE EFFECTS OF M**A:
• Blurred vision
• Chills
• Dangerous increase in body temperature (hyperpyrexia)
• Dehydration, which can be severe
• Feeling faint
• High blood pressure (hypertension)
• Muscle tension and cramping
• Nausea and vomiting
• Restless legs
• Sweating
• Tremors
WITHDRAWAL
The effects of ecstasy often persist for 3-6 hours; however, individuals may administer a further dose when the effects of the previous dose diminish or engage in a binge pattern, consuming multiple doses consecutively. Following around one week of such usage, individuals may have difficulties like irritability, impulsivity, sleep disruptions, anxiety, memory and attention deficits, and diminished motivation in sexual activity.
Upon cessation of ecstasy usage, certain individuals with a history of recurrent use report experiencing withdrawal symptoms, which may encompass:
● Fatigue.
● Depression.
● Difficulty concentrating.
● Loss of appetite.
● Sleep issues.
● Anxiety.
● Irritability.
RECOVERY
Although the United States Food and Drug Administration (FDA) has not yet approved any drugs for the treatment of ecstasy addiction, medical detox can create a stable, safe environment in which any remaining acute intoxication and ecstasy withdrawal can be managed more effectively.18 Detox is typically the first step towards recovery and is insufficient on its own to support long-term rehabilitation. As a result, treatment continues after detox and can take place in a variety of settings.
Inpatient rehab centres offer high-quality care and may be effective if you have a history of polysubstance abuse or co-occurring mental health disorders. You will reside on-site and receive several therapies, along with round-the-clock support and monitoring.
Outpatient rehabilitation allows you to live at home or in a sober-living facility while receiving treatment one to several times each week. It may be an appropriate alternative if you have a supportive home environment or require less intensive treatment.
Cognitive-behavioural therapy is the primary treatment for ecstasy addiction. These approaches help people change beliefs and behaviours that contribute to substance abuse and teach healthy coping strategies for stress and other life challenges. Cognitive-behavioural therapies can be delivered in individual counselling sessions or in group therapy. Mutual-help groups can be an effective complement to cognitive-behavioural therapy, as they provide support from people who are also in recovery.
RECOMMENDED ACTIONS (AGENCIES & STAKEHOLDERS)
LAW ENFORCEMENT
• Increase patrols and surveillance in entertainment hubs
• Monitor micro-distribution networks and vehicle-based supply points
• Strengthen intelligence-sharing with venue security teams
HEALTH SECTOR
• Alert emergency departments to potential M**A-related presentations
• Monitor for clusters of acute intoxication
• Ensure rapid reporting to GUYDIN/EWS
EDUCATION & PREVENTION AGENCIES
• Issue youth-friendly advisories
• Integrate stimulant-risk messaging into school and tertiary outreach
• Engage nightlife operators for awareness support
ADDITIONAL CONSIDERATIONS REGARDING SEIZED PRODUCTS
See the picture below.
In accordance with Schedule I of the Narcotic Drugs and Psychotropic Substances (Control) Act, Cap. 10:10, ecstasy (M**A) is classified as a prohibited substance under the laws of Guyana. Any criminal offence involving the possession, trafficking, or distribution of ecstasy is illegal.
EWS NOTICE LEVEL
⚠️ Level 3 - Emerging Circulation Confirmed
M**A has been forensically validated and detected in a context suggesting active distribution. Continued monitoring is required.
REFERENCES
https://americanaddictioncenters.org/ecstasy-abuse/withdrawal-symptoms
https://www.dea.gov/sites/default/files/2025-01/Ecstasy-M**A-2024-Drug-Fact-Sheet.pdf
https://www.webmd.com/mental-health/addiction/what-is-ecstasy