24/10/2026
| Impact & Outcomes
ARC Onderstepoort Veterinary Research: Rabies Laboratory
Rabies is a fatal viral disease that affects mammals, including humans. It is transmitted through the saliva of an infected animal, usually via bites or scratches, or when infected saliva comes into direct contact with mucous membranes, such as the eyes and mouth, or open wounds.
The ARC Onderstepoort Veterinary Research (ARC-OVR) Rabies Laboratory serves as South Africa’s national reference laboratory for rabies surveillance, diagnostics and research, recognised by the Department of Agriculture (DoA). It is also designated as the World Organisation for Animal Health (WOAH) Reference Laboratory for Rabies in Africa.
For decades, the laboratory has conducted diagnostic testing and research on lyssaviruses in South Africa. This work supports national and provincial governments in developing and implementing rabies control strategies in affected areas, contributing to efforts to protect both animal and human health.
The laboratory also plays an important role in international animal health and travel. Recognised by the European Commission as one of the laboratories involved in pet export certification, it helps South African citizens meet the necessary requirements when travelling internationally with their pets.
Beyond South Africa’s borders, the laboratory contributes to strengthening rabies diagnostic capacity across the continent. As a WOAH reference laboratory, it supports the development of expertise in rabies diagnosis and surveillance among regional laboratories in the Southern African Development Community (SADC) and elsewhere in Africa. It also provides confirmatory testing and training to strengthen the skills and capabilities of laboratory personnel across the region.
Through its research, diagnostic services and capacity-building initiatives, the ARC-OVR Rabies Laboratory continues to contribute to rabies surveillance, improved disease control and the protection of animal and human health across Africa.
